ELISA Piezo1 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Pore-forming subunit of a mechanosensitive non-specific cation channel(PubMed:23479567, PubMed:23695678). Generates currents characterized by a linear current-voltage relationship that are sensitive to ruthenium red and gadolinium. Plays a key role in epithelial cell adhesion by maintaining integrin activation throµgh R-Ras recruitment to the ER, most probably in its activated state, and subsequent stimµLation of calpain signaling(PubMed:20016066). In the kidney, may contribute to the detection of intraluminal pressure changes and to urine flow sensing. Acts as shear-stress sensor that promotes endothelial cell organization and alignment in the direction of blood flow throµgh calpain activation(PubMed:25119035). Plays a key role in blood vessel formation and vascµLar structure in both development and adµLt physiology(By similarity). Immunogen:family with sequence similarity 38, member A Synonyms:FAM38A, KIAA0233 Observed MW:250kd Uniprot ID:Q92508 Reactivity:, Mouse Tested Application:ELISA, WB,IHC Recommended dilution: WB: 1:200-1:1000; IHC: 1:50-1:500 Gene ID:9780 Research Area: