ELISA PLG anti-

Quantity :100µL Clone Number: Aliases:Plasmin antibody; Plasmin heavy chain A antibody; Plasmin light chain B antibody; Plasminogen antibody; PLG antibody; PLMN_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P00747 Immunogen:SyntheQuantityd peptide derived from N-terminal of PLG. Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovµLation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modµLated by CSPG4. Binds to cells. Angiostatin is an angiogenesis inhibitor that blocks neovascµLarization and growth of experimental primary and metastatic tumors in vivo. Petersen T.E., J. Biol. Chem. 265:6104-6111(1990). Forsgren M., FEBS Lett. 213:254-260(1987). Browne M.J., Submitted (OCT-1991) to the EMBL/GenBank/DDBJ databases. Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:PLG Research Areas:Cancer?CardiovascµLar?Cell biology