ELISA MEMO1 anti-

Quantity :50µL Clone Number: Aliases:C21orf19-like protein antibody; C2orf4 antibody; CGI 27 antibody; DKFZp434I0135 antibody; FLJ25031 antibody; HCV NS5A-transactivated protein 7 antibody; Hepatitis C virus NS5A-transactivated protein 7 antibody; Mediator of cell motility 1 antibody; Mediator of ErbB2-driven cell motility 1 antibody; MEMO antibody; Memo-1 antibody; memo1 antibody; MEMO1_ antibody; NS5ATP7 antibody; Protein MEMO1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9Y316 Immunogen:Recombinant Protein MEMO1 protein (1-297AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200 Background:May control cell migration by relaying extracellµLar chemotactic signals to the microtubµLe cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubµLes at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regµLation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubµLe capture and stabilization. Is required for breast carcinoma cell migration. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:MEMO1 Research Areas:Signal transduction