ELISA NUF2 anti-
Quantity :50µL
Clone Number:
Aliases:Cancer/testis antigen 106 antibody; CDCA 1 antibody; CDCA1 antibody; Cell division cycle associated 1 antibody; Cell division cycle associated protein 1 antibody; Cell division cycle-associated protein 1 antibody; CT106 antibody; hNuf 2 antibody; hNuf2 antibody; hNuf2R antibody; hsNuf2 antibody; Kinetochore protein Nuf2 antibody; Nuf 2 antibody; NUF2 antibody; NUF2 NDC80 kinetochore complex component antibody; NUF2 NDC80 kinetochore complex component homolog antibody; NUF2, S. cerevisiae, homolog of antibody; NUF2_ antibody; NUF2R antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:Q9BZD4
Immunogen:Recombinant Kinetochore protein Nuf2 protein (165-464AA)
Raised in:Rabbit
Reactivity:
Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200
Background:Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:12438418, PubMed:14654001, PubMed:15062103, PubMed:15235793, PubMed:15239953, PubMed:15548592, PubMed:17535814). Required for kinetochore integrity and the organization of stable microtubµLe binding sites in the outer plate of the kinetochore (PubMed:15548592). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubµLes and may allow the NDC80 complex to track depolymerizing microtubµLes (PubMed:23085020).
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen Affinity Purified
Conjµgate:Non-conjµgated
Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:NUF2
Research Areas:Cell biology