ELISA RNF20 anti-
Quantity :50µL
Clone Number:
Aliases:BRE1 A antibody; BRE1 antibody; BRE1 E3 ubiquitin ligase homolog antibody; BRE1-A antibody; BRE1A antibody; BRE1A_ antibody; E3 ubiquitin-protein ligase BRE1A antibody; hBRE1 antibody; Homolog of S. cerevisiae BRE1 antibody; RING finger protein 20 antibody; Ring finger protein 20 E3 ubiquitin protein ligase antibody; Rnf20 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:Q5VTR2
Immunogen:Fusion protein of RNF20
Raised in:Rabbit
Reactivity:, Mouse
Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:100
Background:The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this gene is an E3 ubiquitin ligase that regµLates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regµLates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen affinity purification
Conjµgate:Non-conjµgated
Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:RNF20
Research Areas:Cell biology