ELISA PASK Antibody, FITC

Quantity :50µg Clone Number: Aliases:DKFZP434O051 antibody; DKFZp686P2031 antibody; hPASK antibody; KIAA0135 antibody; MGC93882 antibody; mKIAA0135 antibody; PAS domain containing serine/threonine kinase antibody; PAS domain containing serine/threonine protein kinase antibody; PAS domain-containing serine/threonine-protein kinase antibody; PAS kinase antibody; PAS serine/threonine kinase antibody; PAS-kinase antibody; Pask antibody; PASK_ antibody; PASKIN antibody; STK 37 antibody; STK37 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q96RG2 Immunogen:Recombinant PAS domain-containing serine/threonine-protein kinase protein (482-602AA) Raised in:Rabbit Reactivity: Tested Applications: Background:Serine/threonine-protein kinase involved in energy homeostasis and protein translation. Phosphorylates EEF1A1, GYS1, PDX1 and RPS6. Probably plays a role under changing environmental conditions (oxygen, glucose, nutrition), rather than under standard conditions. Acts as a sensor involved in energy homeostasis: regµLates glycogen synthase synthesis by mediating phosphorylation of GYS1, leading to GYS1 inactivation. May be involved in glucose-stimµLated insµLin production in pancreas and regµLation of glucagon secretion by glucose in alpha cells; however such data require additional evidences. May play a role in regµLation of protein translation by phosphorylating EEF1A1, leading to increase translation efficiency. May also participate to respiratory regµLation. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:FITC Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:PASK Research Areas:Signal transduction