ELISA KMT5C anti-
Quantity :50µL
Clone Number:
Aliases:Histone-lysine N-methyltransferase KMT5C (EC 2.1.1.43) (Lysine N-methyltransferase 5C) (Lysine-specific methyltransferase 5C) (Suppressor of variegation 4-20 homolog 2) (Su(var)4-20 homolog 2) (Suv4-20h2), KMT5C, SUV420H2
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:Q86Y97
Immunogen:Recombinant Histone-lysine N-methyltransferase KMT5C protein (235-345aa)
Raised in:Rabbit
Reactivity:
Tested Applications:ELISA, WB, IF; Recommended dilution: WB:1:1000-1:5000, IF:1:100-1:500
Background:Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. KMT5C is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2) (By similarity).
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjµgate:Non-conjµgated
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:KMT5C
Research Areas:Epigenetics and Nuclear Signaling