ELISA ORF1 Antibody, HRP

Quantity :50µg Clone Number: Aliases:ORF1 antibody; Non-structural polyprotein pORF1 [Includes: Methyltransferase antibody; EC 2.1.1.- antibody; EC 2.7.7.-); Putative papain-like cysteine protease antibody; PLP antibody; EC 3.4.22.-); NTPase/helicase antibody; EC 3.6.4.-); RNA-directed RNA polymerase antibody; RdRp antibody; EC 2.7.7.48)] antibody Product Type:Polyclonal Antibody Immunogen Species:Hepatitis E virus genotype 1 (isolate Homo sapiens ()/Pakistan/Sar-55) (HEV-1) UniProt ID:P33424 Immunogen:Recombinant Hepatitis E virus genotype 1 Non-structural polyprotein pORF1 protein (60-240AA) Raised in:Rabbit Reactivity:Hepatitis E virus genotype 1 Tested Applications:ELISA Background:Methyltransferase displays a cytoplasmic capping enzyme activity. This function is necessary since all viral RNAs are syntheQuantityd in the cytoplasm, and host capping enzymes are restricted to the nucleus. The enzymatic reaction involves a covalent link between 7-methyl-GMP and the methyltransferase, whereas eukaryotic capping enzymes form a covalent complex only with GMP. Methyltransferase catalyzes transfer of a methyl group from S-adenosylmethionine to GTP and GDP to yield m7GTP or m7GDP. GMP, GpppG, and GpppA were poor substrates for the methyltransferase. This enzyme also displays guanylyltransferase activity to form a covalent complex, methyltransferase-m7GMP, from which 7-methyl-GMP is transferred to the mRNA to create the cap structure. Cap analogs such as m7GTP, m7GDP, et2m7GMP, and m2et7GMP inhibit the methyltransferase reaction (By similarity). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ORF1 Research Areas:Others