ELISA EDN3 anti-

Quantity :50µL Clone Number: Aliases:EDN3 antibody; EDN3_ antibody; Endothelin 3 antibody; Endothelin-3 antibody; ET 3 antibody; ET-3 antibody; PPET3 antibody; Preproendothelin 3 antibody; Preproendothelin-3 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P14138 Immunogen:Fusion protein of EDN3 Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:25-1:100 Background:The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:EDN3 Research Areas:Neuroscience?Cancer;Signal transduction