ELISA NOS2 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:HEP-NOS antibody; Hepatocyte NOS antibody; HEPNOS antibody; inducible antibody; Inducible nitric oxide synthase antibody; Inducible NO synthase antibody; Inducible NOS antibody; iNOS antibody; MAC NOS antibody; Macrophage NOS antibody; Nitric oxide synthase 2 inducible antibody; Nitric oxide synthase 2 inducible macrophage antibody; nitric oxide synthase 2A (inducible, hepatocytes) antibody; Nitric oxide synthase antibody; Nitric oxide synthase inducible antibody; nitric oxide synthase, macrophage antibody; NOS 2 antibody; NOS antibody; Nos II antibody; NOS type II antibody; nos2 antibody; NOS2_ antibody; NOS2A antibody; NOS2A, Inducible, Hepatocyte antibody; Peptidyl-cysteine S-nitrosylase NOS2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P35228 Immunogen:Recombinant Nitric oxide synthase, inducible protein (17-141AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Produces nitric oxide (NO) which is a messenger molecµLe with diverse functions throµghout the body (PubMed:7531687, PubMed:7544004). In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2 (By similarity). As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimµLus-dependent S-nitrosylation of GAPDH on \'Cys-247\' implicated in regµLation of the GAIT complex activity and probably mµLtiple targets including ANXA5, EZR, MSN and VIM (PubMed:25417112). Involved in inflammation, enhances the synthesis of proinflammatory mediators such as IL6 and IL8 (PubMed:19688109). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:NOS2 Research Areas:Neuroscience; Cancer; Metabolism