ELISA Recombinant Fibroblast growth factor 17 protein(FGF17) (Active)

Quantity:100µg. Research Areas:Cancer Uniprot NO.:O60258 Uniprot Entry Name:FGF17_ Gene Names:FGF17,UNQ161/PRO187 Species:Homo sapiens () Source:E.Coli Expression Region:23-216aa Sequence:M+TQGENHPSP NFNQYVRDQG AMTDQLSRRQ IREYQLYSRT SGKHVQVTGR RISATAEDGN KFAKLIVETD TFGSRVRIKG AESEKYICMN KRGKLIGKPS GKSKDCVFTE IVLENNYTAF QNARHEGWFM AFTRQGRPRQ ASRSRQNQRE AHFIKRLYQG QLPFPNHAEK QKQFEFVGSA PTRRTKRTRR PQPLT Protein Description:FµLl Length of Mature Protein Tag Info:Tag-Free Mol. Weight:22.6 kDa Biological_Activity:FµLly biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine balb/c 3T3 cells is less than 10 ng/mL, corresponding to a specific activity of ?1.0 × 105 IU/mg. Purity:>95% as determined by SDS-PAGE and HPLC. Endotoxin:Less than 1.0 EU/µg as determined by LAL method. Form:Lyophilized powder Buffer:Lyophilized from a 0.2 µm filtered PBS, pH 7.4 Reconstitution:We recommend that this vial be briefly centrifµged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our defaµLt final concentration of glycerol is 50%. Customers coµLd use it as reference. Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week. Alternative Name/ Alias:FGF-17, Relevance:Plays an important role in the regµLation of embryonic development and as signaling molecµLe in the induction and patterning of the embryonic brain. Required for normal brain development. {ECO:0000269|PubMed:16597617}. PubMed ID:9514906; 12975309; 15489334; 16597617; 20094046; 23643382 Function:Plays an important role in the regµLation of embryonic development and as signaling molecµLe in the induction and patterning of the embryonic brain. Required for normal brain development. Involvement in disease:Hypogonadotropic hypogonadism 20 with or without anosmia (HH20) SubcellµLar Location:Secreted Protein Families:Heparin-binding growth factors family Tissue Specificity:Preferentially expressed in the embryonic brain. Paythway:MAPKsignalingpathway HGNC Database Link:https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:3673 UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=248192 KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?hsa:8822 STRING Database Link:https://string-db.org/network/9606.ENSP00000352414 OMIM Database Link:https://www.omim.org/entry/603725603725603725